Even though patches or update is actually a good thing, it can still cause problems. However, there are some tips to avoid problems as much as possible.

1. Wait a bit
2. Save your progress (save and tray folder)
3. Check your save folder for modding files
4. Empty your mods folder
5. After update repair or verify
6. Delete your localtumbcash.packet file
7. Wait for ok from modders You can check your mods with Scarletsrealm or Luthienrising Mod & CC Issues

There is a more detailed instruction on Omisimmts Patreon for members (also free members).